Have been testing Microsoft Beta APIs for kinect with the kinect Toolkit. To create an appliation that catch a users gesture is very easy. As a GIS developer it feels like it would integrate perfectly with ESRI ArcGIS for WPF, to build for example kiosk applications where a user can interact with a map. What gestures would make sense for a user to navigate a map?
Recent publication from IJHG (open access) might be of some help:
But I'm really waiting for somebody to integrate MYO into my GIS desktop!
These are quite good (and tested, as mentionned in the video), made with the WPF toolkit: http://www.youtube.com/watch?v=Uj3z6bhcSsM
One caveat about the Kinect is that it uses full body gestures: the skeleton detection from the official Kinect SDK is very innacurate if it can see only part of your body (e.g. sitting at your desk), however if you need that, OpenNI instead of the official SDK could be helpful).