I am working on project to create a DSM raster for whole Kentucky. I will have over 46000 tiff tiles and each one is about 10 Mb and one band. Normally, I use Mosaic to New Raster Tool but this time data is very large. I am planning to divide the project into smaller pieces but I have no idea what size should I set the each piece. I will use python code with ArcGis Desktop 10.6 to complete project. Considering my computer has 2.7 Ghz (i7) processor with 16 Gb RAM, How many tiles I need to use at one time? like 1000? 10000? or what number?