I'm trying to open a .ply file (point cloud in ArcGIS Desktop and ArcGIS Pro), but I can't.
How can I convert the .ply file to .las, or open .ply in ArcGIS Desktop or ArcGIS Pro?
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You can convert the .ply files (aka Polygon File Format) to .las with other software, and then, import it in ArcGIS.
LAStools: supports conversion of ASCII .ply files (treats it as text file) with
las2las tool (see here).