Since upgrading to ArcGIS Pro 2.8 from 2.6, I am facing an issue with the Jupyter Notebook that fails to load and returns an error:

Failed to Load Notebook

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What all I have tried:

  1. Tried opening the notebook from the Python command prompt it gives an error as DLL Load failed the specified procedure could not be found
  2. Tried cloning the default environment from the manage environment option in the Python package manager of ArcGIS Pro by Project tab>> Python>> Manage environments>> clone>> assigned new name and path as C:\Temp.
  3. Renamed the python folder from 'C:\Program Files\ArcGIS\Pro\bin\Python'
  4. Tried repairing the application from the control panel
  5. Renamed the ArcGIS Pro folder from C:\Users<computer name>\AppData\Roaming\ESRI, and C:\Users<computer name>\AppData\Local\ESRI
  6. Renamed the FLEXnet folder C:\ProgramData\FLEXnet.
  7. Renamed the ArcGIS Pro folder from the registry editor as well
  8. Tried adding exclusions in the antivirus software for ArcGIS Pro with the help of the IT team
  9. Also tried running it from the location C:\Program Files\ArcGIS\Pro\bin\Python\envs\arcgispro-py3\Scripts but reproduced the same error message
  10. Checked if there are any Python variables defined from the Environment variables settings

Any insights or suggestions on how to resolve this error?

2 Answers 2


When I'm going to give up, I tried to reboot the computer and it worked. You should really try this. Let me know if this works.


https://support.esri.com/en/technical-article/000022938 This may be something related to permissions and exclusions from your antivirus software.

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