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This question already has an answer here:

How does one remove the border and legend of a 1:50 000 map? Want to combine several maps to form one.

marked as duplicate by AndreJ, whuber Feb 4 '14 at 14:40

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You can use a function Raster > Extraction > Clipper in QGIS. There you can define a mask layer from shapefile, or use coordinates of corners.

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