I had the same problem. The inconvenient is that QGIS seems that is not able to understand correctly the projection information stored on the .jp2 image files. I recommend you to follow these steps: (This worked on QGIS 3.10 A Coruña) 1. Open an empty QGIS project file. 2. Create a new projection by going to "preferences" -> "personalize projection". [![enter image description here][1]][1] 3. Go to [spatialreference.org][2] to search the projections used for Mars. 4. The projection usually used by NASA and the USGS for Mars is the IAU2000:49910: Mars Equidistant Cylindrical. We should add this projection on QGIS. 5. Click on the IAU2000:49910 and then click on "Well Known Text as HTML". 6. Copy that text, which should be: > PROJCS["Mars_Equidistant_Cylindrical", > GEOGCS["Mars 2000", > DATUM["D_Mars_2000", > SPHEROID["Mars_2000_IAU_IAG",3396190.0,169.89444722361179]], > PRIMEM["Greenwich",0], > UNIT["Decimal_Degree",0.0174532925199433]], > PROJECTION["Equidistant_Cylindrical"], > PARAMETER["False_Easting",0], > PARAMETER["False_Northing",0], > PARAMETER["Central_Meridian",0], > PARAMETER["Standard_Parallel_1",0], > UNIT["Meter",1]] This code defines the ellipsoid and the projection for Mars. 7. Return to QGIS and paste on the opened window and give it an easy name to identify: [![enter image description here][3]][3] (Remember the format must be: WKT - Welll Known Text) 9. Load the ESP_036925_1985_(COLOR/RED) images. Ignore possible errors about projections. 10. Now change **the project projection** to IAU2000:49910. The images now should be correctly georeferenciatied: [![enter image description here][4]][4] If this doesn't worked for you, I would recommend to update to a newer version of QGIS and try it again. I hope this helped you, sorry for my English. [1]: https://i.sstatic.net/RFfsM.png [2]: https://spatialreference.org/ref/?search=mars [3]: https://i.sstatic.net/OVOQa.png [4]: https://i.sstatic.net/LPZFY.jpg