I think this blog post on the Esri site is still applicable:

[ArcObjects or the ArcGIS Runtime SDKs for Java and WPF—which is right for you?][1]

Though [this question][2] discusses the Java flavors, it may help as well.


  [1]: http://blogs.esri.com/esri/arcgis/2012/12/07/arcobjects-or-runtime-sdk/
  [2]: http://gis.stackexchange.com/questions/110210/difference-between-arcobjects-sdk-for-java-and-arcgis-runtime-for-java