I too can replicate the issue in Modelbuilder. The help files states for the [raster layer parameter][1]: *The process_as_multidimensional parameter is only supported when the input is a single, multidimensional raster.* Your model implies it is getting a dataset (so no necessarily a CRF file) or the CRF is not what you think it is. I think more research of this [page][2] might help you? [1]: https://pro.arcgis.com/en/pro-app/latest/tool-reference/spatial-analyst/sample.htm#GUID-5BCFEE6A-BC32-40FF-8082-092C63218195 [2]: https://pro.arcgis.com/en/pro-app/latest/help/data/imagery/an-overview-of-multidimensional-raster-data.htm