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I just upgraded ArcGIS Pro to version 2.2 from within the application. After the upgrade, when I open a project, this dialog comes up:

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Also, the Python window shows this:

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Finally, I cannot seem to see any toolboxes in the geoprocessing window.

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Am I going to have to uninstall and reinstall to fix this? Or is there some other way?

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3 Answers 3

Reset to default
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Try this if you're willing:

  1. get the latest version of the pro msi (http://links.esri.com/pro/download/current)
  2. Run the msi and choose the repair option
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I can offer no explanation as to what may have gone astray with your upgrade because mine from 2.1.3 to 2.2.0 went without a hitch.

However, with the Python window failing to initialize I think the quick fix will be to uninstall/reinstall ArcGIS Pro which should make sure that it can find Python 3.6.5 in the expected location.

I am sure that there will be other ways to fix this but the above procedure should have you up and back running in 30-60 minutes.

One of your symptoms seems to match that at Toolboxes not appearing in ArcGIS Pro? so I am mentioning that question here in case resolving your or that question sheds any light on the other.

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    Using @gotchula's solution, I had it up and running properly in just a few minutes. The longest part of the process was downloading the 1.1GB file.
    – Fezter
    Commented Jul 3, 2018 at 5:07
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    @Fezter as soon as I saw that second answer I was pretty sure it would work and be quicker than mine so I'm glad it got to you in time.
    – PolyGeo ♦
    Commented Jul 3, 2018 at 5:10
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If these solutions don't work, this was a simple fix: https://support.esri.com/en/technical-article/000022262

Clear cache

Clear all cache files in the AppData folder, and relaunch ArcGIS Pro.

C:\Users<username>\AppData\Local\ESRI\Local Caches

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  • Encountered this in 2.7.3. Solved the issue without going through a reinstall
    – Eok
    Commented Jul 28, 2021 at 21:50

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